Investigation Title MAQC Illumina data set (excerpt) Experimental Design array_platform_variation_design Experimental Factor Name SAMPLE Experimental Factor Type Sample Experimental Factor Type Term Source REF MGED Ontology Person Last Name Shi Person First Name Leming Person Roles submitter Person Roles Term Source REF MGED Ontology Quality Control Types technical_replicate Quality Control Types Term Source REF MGED Ontology Public Release Date 08/09/2006 Comment[ArrayExpressSubmissionDate] 02/08/2006 Publication Author List Leming Shi, Laura H. Reid, Richard Shippy, Janet A. Warrington, William Slikker Jr. Publication Title The MicroArray Quality Control (MAQC) project demonstrates concordant results between gene expression technology platforms Experiment Description The MicroArray Quality Control (MAQC) project was initiated to address these concerns, as well as other performance and analysis issues. We demonstrate the consistency of results within a platform across test sites as well as the high level of cross-platform concordance in terms of genes identified as differentially expressed. The MAQC study provides a rich resource that will help build consensus on the use of microarrays in research, clinical and regulatory settings. Manuscripts related to the MAQC project have been published in Nature Biotechnology, 24(9), September, 2006. More information about the MAQC project can be found at http://edkb.fda.gov/MAQC/. Protocol Name P-EXML-1 Protocol Type transformation Protocol Description Data was processed using Illumina BeadStudio version 1.5.0.34 software using background subtraction and cubic spline normalization Protocol Term Source REF MGED Ontology SDRF File illumina_sdrf.txt Term Source Name MGED Ontology Term Source File http://mged.sourceforge.net/ontologies/MGEDontology.php