Experiment section domain ebi.ac.uk accession E-TABM-136 quality_control biological_replicate_design experiment_design_type organism_part_comparison_design;species_comparison_design; name Functionality of Intergenic Transcription: An Evolutionary Comparison description "Although a large proportion of human transcription occurs outside the boundaries of known genes, the functional significance of this transcription remains unknown. We have compared the expression patterns of known genes as well as intergenic transcripts within the ENCODE regions between humans and chimpanzees in brain, heart, testis and lymphoblastoid cell lines. We find that intergenic transcripts show patterns of tissue-specific conservation of their expression which are comparable to exonic transcripts of known genes. This suggests that intergenic transcripts are subject to functional constraints that restrict their rate of evolutionary change as well as putative positive selection to an extent comparable to that of classical protein-coding genes. In brain and testis, we find that part of this intergenic transcription is caused by wide-spread use of alternative promoters. Further, we find that about half of the expression differences between humans and chimpanzees are due to intergenic transcripts. In order to transfer genetic information encoded in the genomic sequence of an organism into functional features, the genomic sequence must be transcribed. According to the current genome annotation, the human genome produces transcripts from 20,000–25,000 protein-coding genes and a smaller number of non-coding genes. Recently, the introduction of tiling arrays that enable the measurement of transcription regardless of previous annotation challenged this view by providing evidence that a large proportion of transcription occurs outside of annotated genes. It has been suggested that these transcripts represent previously unidentified functional RNAs as well as extensions of known genes. However, their lack of conservation between species on the DNA sequence level raises questions about their functionality. In this study we assess the functionality of these novel transcripts by testing the extent to which their expression is conserved between humans and chimpanzees in different tissues. Surprisingly, we find the expression of known and novel transcripts to be conserved to the same relative extent when different tissues are compared. This suggests that both known and novel transcripts are equally affected by adaptive and stabilizing selection in different tissues during human and chimpanzee evolution. Further, in terms of absolute numbers, about half of the expression differences between humans and chimpanzees in any given tissue are due to intergenic transcripts." ArrayExpressDisplayName "Transcription profiling of human and chimpanzee heart, brain, testis and lymphblastoid cell lines to study functionality of intergenic transcription." release_date 2006-09-30 submission_date 2006-08-18 submitter Philipp Khaitovich submitter_email khaitovich@eva.mpg.de publication_title Functionality of Intergenic Transcription: An Evolutionary Comparison authors Philipp Khaitovich; Janet Kelso; Henriette Franz; Johann Visagie; Thomas Giger; Sabrina Joerchel; Ekkehard Petzold; Richard E. Green; Michael Lachmann; Svante Pääbo journal PLoS Genetics volume issue pages year 2006 Protocol section accession type text name P-TABM-47 labeling Following Affymetrix Whole Transcript (WT) Sense Target Labeling Assay protocol. Starting amount of material: 2 ug of total RNA per sample Whole Transcript (WT) Sense Target Labeling Assay Hybridization section File[raw] File[exp] Array[serial] Array[accession] Protocol[extraction] Protocol[labeling] Protocol[hybridization] Protocol[scanning] BioSource BioSourceMaterial BioMaterialCharacteristics[Organism] BioMaterialCharacteristics[Sex] BioMaterialCharacteristics[Age(years)] BioMaterialCharacteristics[OrganismPart] BioMaterialCharacteristics[OrganismStatus] FactorValue[Organism] FactorValue[OrganismPart] FactorValue[lymphoblastoid cellLine] CB1F.CEL CB1F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c01 organism_part Pan troglodytes male 7 "brain, prefrontal cortex" postmortem Pan troglodytes brain CB2F.CEL CB2F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c02 organism_part Pan troglodytes male 12 "brain, prefrontal cortex" postmortem Pan troglodytes brain CB3F.CEL CB3F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c03 organism_part Pan troglodytes male 12 "brain, prefrontal cortex" postmortem Pan troglodytes brain CB4F.CEL CB4F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c04 organism_part Pan troglodytes male 12 "brain, prefrontal cortex" postmortem Pan troglodytes brain CB5F.CEL CB5F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c05 organism_part Pan troglodytes male >40 "brain, prefrontal cortex" postmortem Pan troglodytes brain CC1F.CEL CC1F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c06 organism_part Pan troglodytes female 19 lymphoblastoid cell line postmortem Pan troglodytes lymphoblastoid cell line CC2F.CEL CC2F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c07 organism_part Pan troglodytes female 20 lymphoblastoid cell line postmortem Pan troglodytes lymphoblastoid cell line CC3F.CEL CC3F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c08 organism_part Pan troglodytes female 32 lymphoblastoid cell line postmortem Pan troglodytes lymphoblastoid cell line CC4F.CEL CC4F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c09 organism_part Pan troglodytes female 12 lymphoblastoid cell line postmortem Pan troglodytes lymphoblastoid cell line CC5F.CEL CC5F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c10 organism_part Pan troglodytes female 37 lymphoblastoid cell line postmortem Pan troglodytes lymphoblastoid cell line CH1F.CEL CH1F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c01 organism_part Pan troglodytes male 7 heart muscle postmortem Pan troglodytes heart CH2F.CEL CH2F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c11 organism_part Pan troglodytes male 34 heart muscle postmortem Pan troglodytes heart CH3F.CEL CH3F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c03 organism_part Pan troglodytes male 12 heart muscle postmortem Pan troglodytes heart CH4F.CEL CH4F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c12 organism_part Pan troglodytes male 26 heart muscle postmortem Pan troglodytes heart CH5F.CEL CH5F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c02 organism_part Pan troglodytes male 12 heart muscle postmortem Pan troglodytes heart CT1F.CEL CT1F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c13 organism_part Pan troglodytes male 20 testis postmortem Pan troglodytes testis CT2F.CEL CT2F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c02 organism_part Pan troglodytes male 12 testis postmortem Pan troglodytes testis CT3F.CEL CT3F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c03 organism_part Pan troglodytes male 12 testis postmortem Pan troglodytes testis CT4F.CEL CT4F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c04 organism_part Pan troglodytes male 12 testis postmortem Pan troglodytes testis CT5F.CEL CT5F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c05 organism_part Pan troglodytes male >40 testis postmortem Pan troglodytes testis HB1F.CEL HB1F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h01 organism_part Homo sapiens male 45 "brain, prefrontal cortex" postmortem Homo sapiens brain HB2F.CEL HB2F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h02 organism_part Homo sapiens male 45 "brain, prefrontal cortex" postmortem Homo sapiens brain HB3F.CEL HB3F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h03 organism_part Homo sapiens male 48 "brain, prefrontal cortex" postmortem Homo sapiens brain HB4F.CEL HB4F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h04 organism_part Homo sapiens male 56 "brain, prefrontal cortex" postmortem Homo sapiens brain HB5F.CEL HB5F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h05 organism_part Homo sapiens male 67 "brain, prefrontal cortex" postmortem Homo sapiens brain HC1F.CEL HC1F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h06 organism_part Homo sapiens female 13 lymphoblastoid cell line postmortem Homo sapiens lymphoblastoid cell line HC2F.CEL HC2F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h07 organism_part Homo sapiens female 12 lymphoblastoid cell line postmortem Homo sapiens lymphoblastoid cell line HC3F.CEL HC3F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h08 organism_part Homo sapiens female 20 lymphoblastoid cell line postmortem Homo sapiens lymphoblastoid cell line HC4F.CEL HC4F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h09 organism_part Homo sapiens female 22 lymphoblastoid cell line postmortem Homo sapiens lymphoblastoid cell line HC5F.CEL HC5F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h10 organism_part Homo sapiens female 32 lymphoblastoid cell line postmortem Homo sapiens lymphoblastoid cell line HH1F.CEL HH1F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h11 organism_part Homo sapiens male 71 heart muscle postmortem Homo sapiens heart HH2F.CEL HH2F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h12 organism_part Homo sapiens male 74 heart muscle postmortem Homo sapiens heart HH3F.CEL HH3F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h13 organism_part Homo sapiens male 57 heart muscle postmortem Homo sapiens heart HH4F.CEL HH4F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h14 organism_part Homo sapiens male 77 heart muscle postmortem Homo sapiens heart HH5F.CEL HH5F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h15 organism_part Homo sapiens male 51 heart muscle postmortem Homo sapiens lymphoblastoid cell line HT1F.CEL HT1F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h16 organism_part Homo sapiens male 27 testis postmortem Homo sapiens testis HT2F.CEL HT2F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h17 organism_part Homo sapiens male 32 testis postmortem Homo sapiens testis HT3F.CEL HT3F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h18 organism_part Homo sapiens male 25 testis postmortem Homo sapiens testis HT4F.CEL HT4F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h19 organism_part Homo sapiens male 41 testis postmortem Homo sapiens testis HT5F.CEL HT5F.EXP 4011140 A-AFFY-61 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h20 organism_part Homo sapiens male 27 testis postmortem Homo sapiens testis CB1R.CEL CB1R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c01 organism_part Pan troglodytes male 7 "brain, prefrontal cortex" postmortem Pan troglodytes brain CB2R.CEL CB2R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c02 organism_part Pan troglodytes male 12 "brain, prefrontal cortex" postmortem Pan troglodytes brain CB3R.CEL CB3R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c03 organism_part Pan troglodytes male 12 "brain, prefrontal cortex" postmortem Pan troglodytes brain CB4R.CEL CB4R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c04 organism_part Pan troglodytes male 12 "brain, prefrontal cortex" postmortem Pan troglodytes brain CB5R.CEL CB5R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c05 organism_part Pan troglodytes male >40 "brain, prefrontal cortex" postmortem Pan troglodytes brain CC1R.CEL CC1R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c06 organism_part Pan troglodytes female 19 lymphoblastoid cell line postmortem Pan troglodytes lymphoblastoid cell line CC2R.CEL CC2R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c07 organism_part Pan troglodytes female 20 lymphoblastoid cell line postmortem Pan troglodytes lymphoblastoid cell line CC3R.CEL CC3R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c08 organism_part Pan troglodytes female 32 lymphoblastoid cell line postmortem Pan troglodytes lymphoblastoid cell line CC4R.CEL CC4R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c09 organism_part Pan troglodytes female 12 lymphoblastoid cell line postmortem Pan troglodytes lymphoblastoid cell line CC5R.CEL CC5R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c10 organism_part Pan troglodytes female 37 lymphoblastoid cell line postmortem Pan troglodytes lymphoblastoid cell line CH1R.CEL CH1R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c01 organism_part Pan troglodytes male 7 heart muscle postmortem Pan troglodytes heart CH2R.CEL CH2R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c11 organism_part Pan troglodytes male 34 heart muscle postmortem Pan troglodytes heart CH3R.CEL CH3R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c03 organism_part Pan troglodytes male 12 heart muscle postmortem Pan troglodytes heart CH4R.CEL CH4R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c12 organism_part Pan troglodytes male 26 heart muscle postmortem Pan troglodytes heart CH5R.CEL CH5R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c02 organism_part Pan troglodytes male 12 heart muscle postmortem Pan troglodytes heart CT1R.CEL CT1R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c13 organism_part Pan troglodytes male 20 testis postmortem Pan troglodytes testis CT2R.CEL CT2R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c02 organism_part Pan troglodytes male 12 testis postmortem Pan troglodytes testis CT3R.CEL CT3R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c03 organism_part Pan troglodytes male 12 testis postmortem Pan troglodytes testis CT4R.CEL CT4R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c04 organism_part Pan troglodytes male 12 testis postmortem Pan troglodytes testis CT5R.CEL CT5R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 c05 organism_part Pan troglodytes male >40 testis postmortem Pan troglodytes testis HB1R.CEL HB1R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h01 organism_part Homo sapiens male 45 "brain, prefrontal cortex" postmortem Homo sapiens brain HB2R.CEL HB2R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h02 organism_part Homo sapiens male 45 "brain, prefrontal cortex" postmortem Homo sapiens brain HB3R.CEL HB3R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h03 organism_part Homo sapiens male 48 "brain, prefrontal cortex" postmortem Homo sapiens brain HB4R.CEL HB4R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h04 organism_part Homo sapiens male 56 "brain, prefrontal cortex" postmortem Homo sapiens brain HB5R.CEL HB5R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h05 organism_part Homo sapiens male 67 "brain, prefrontal cortex" postmortem Homo sapiens brain HC1R.CEL HC1R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h06 organism_part Homo sapiens female 13 lymphoblastoid cell line postmortem Homo sapiens lymphoblastoid cell line HC2R.CEL HC2R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h07 organism_part Homo sapiens female 12 lymphoblastoid cell line postmortem Homo sapiens lymphoblastoid cell line HC3R.CEL HC3R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h08 organism_part Homo sapiens female 20 lymphoblastoid cell line postmortem Homo sapiens lymphoblastoid cell line HC4R.CEL HC4R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h09 organism_part Homo sapiens female 22 lymphoblastoid cell line postmortem Homo sapiens lymphoblastoid cell line HC5R.CEL HC5R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h10 organism_part Homo sapiens female 32 lymphoblastoid cell line postmortem Homo sapiens lymphoblastoid cell line HH1R.CEL HH1R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h11 organism_part Homo sapiens male 71 heart muscle postmortem Homo sapiens heart HH2R.CEL HH2R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h12 organism_part Homo sapiens male 74 heart muscle postmortem Homo sapiens heart HH3R.CEL HH3R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h13 organism_part Homo sapiens male 57 heart muscle postmortem Homo sapiens heart HH4R.CEL HH4R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h14 organism_part Homo sapiens male 77 heart muscle postmortem Homo sapiens heart HH5R.CEL HH5R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h15 organism_part Homo sapiens male 51 heart muscle postmortem Homo sapiens heart HT1R.CEL HT1R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h16 organism_part Homo sapiens male 27 testis postmortem Homo sapiens testis HT2R.CEL HT2R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h17 organism_part Homo sapiens male 32 testis postmortem Homo sapiens testis HT3R.CEL HT3R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h18 organism_part Homo sapiens male 25 testis postmortem Homo sapiens testis HT4R.CEL HT4R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h19 organism_part Homo sapiens male 41 testis postmortem Homo sapiens testis HT5R.CEL HT5R.EXP 4011140 A-AFFY-67 P-TABM-44 P-TABM-47 Affymetrix:Protocol:Hybridization-MES_EukGE-WS2v5_450-DEV P-TABM-46 h20 organism_part Homo sapiens male 27 testis postmortem Homo sapiens testis